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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPF
All Species:
13.64
Human Site:
S2247
Identified Species:
25
UniProt:
P49454
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49454
NP_057427.3
3210
367764
S2247
E
R
E
R
E
N
D
S
L
K
D
K
V
E
N
Chimpanzee
Pan troglodytes
XP_001171549
3114
357698
S2151
E
R
E
R
E
N
D
S
L
K
D
K
V
E
N
Rhesus Macaque
Macaca mulatta
XP_001105956
3113
357422
S2150
E
R
E
R
E
N
D
S
L
K
D
K
V
E
N
Dog
Lupus familis
XP_852813
1449
166096
D583
S
Y
E
T
L
V
Q
D
K
T
Q
G
C
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510329
2965
340022
N2059
C
L
Q
S
Q
L
Q
N
L
D
K
T
M
Q
A
Chicken
Gallus gallus
O42184
1433
161009
F567
M
S
S
L
K
E
K
F
E
S
S
E
E
A
L
Frog
Xenopus laevis
P85120
2058
236320
K1192
S
S
L
K
S
Q
Y
K
S
L
E
Q
A
H
R
Zebra Danio
Brachydanio rerio
XP_002665261
2708
311087
K1842
D
Q
I
S
V
L
L
K
E
K
E
Q
L
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
S824
L
Q
Q
L
Q
S
K
S
A
E
S
E
S
A
L
Honey Bee
Apis mellifera
XP_001120388
2064
240016
H1198
I
D
H
W
K
V
E
H
C
K
F
E
L
D
N
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
H1100
K
K
K
E
S
E
L
H
S
V
S
S
R
L
E
Sea Urchin
Strong. purpuratus
XP_796801
3636
416057
S2476
E
L
Q
E
I
V
E
S
R
K
E
E
I
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25386
1790
206434
E924
A
I
N
E
N
L
E
E
M
K
I
Q
C
N
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
91.4
32.8
N.A.
N.A.
N.A.
N.A.
50.5
20.4
21.5
31.3
N.A.
21.3
22.9
20.1
22
Protein Similarity:
100
96.4
93.8
39.1
N.A.
N.A.
N.A.
N.A.
67.5
32.4
38.6
51.2
N.A.
35.2
41.3
36.4
43.7
P-Site Identity:
100
100
100
6.6
N.A.
N.A.
N.A.
N.A.
6.6
0
0
6.6
N.A.
6.6
13.3
0
20
P-Site Similarity:
100
100
100
13.3
N.A.
N.A.
N.A.
N.A.
40
13.3
20
40
N.A.
46.6
46.6
20
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
8
0
0
0
8
16
16
% A
% Cys:
8
0
0
0
0
0
0
0
8
0
0
0
16
0
0
% C
% Asp:
8
8
0
0
0
0
24
8
0
8
24
0
0
8
8
% D
% Glu:
31
0
31
24
24
16
24
8
16
8
24
31
8
24
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
8
0
0
0
0
16
0
0
0
0
0
8
0
% H
% Ile:
8
8
8
0
8
0
0
0
0
0
8
0
8
8
0
% I
% Lys:
8
8
8
8
16
0
16
16
8
54
8
24
0
0
0
% K
% Leu:
8
16
8
16
8
24
16
0
31
8
0
0
16
16
16
% L
% Met:
8
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% M
% Asn:
0
0
8
0
8
24
0
8
0
0
0
0
0
8
39
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
16
24
0
16
8
16
0
0
0
8
24
0
8
8
% Q
% Arg:
0
24
0
24
0
0
0
0
8
0
0
0
8
0
8
% R
% Ser:
16
16
8
16
16
8
0
39
16
8
24
8
8
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
0
8
0
8
0
0
0
% T
% Val:
0
0
0
0
8
24
0
0
0
8
0
0
24
8
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _